Around 1:30 a.m. shots were fired in the 100 block of West 33rd Street near Barnard Street.
One victim went to a nearby fire stations for help. Police found the other three other victims on West 33rd.
Three men were taken to the hospital in stable condition. The fourth victim, a woman, died.
If you have any information, call CrimeStoppers at 912-234-2020.